EntransterTM-in vivo for RNA

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18668-11-10.5ml$2,199.00

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Description

●Effective and reproducible in vivo RNA delivery with low toxicity.

●Non-viral vector for gene transfer.

●The simplest and safest approach to delivery gene in vivo.

●No detectable inflammatory response.

  1. BRITISH JOURNAL OF PHARMACOLOGY Volume177, Issue14 July 2020 Pages 3258-3272
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  2. Mol Ther Nucleic Acids. 2019 Dec 6;18:1-15.doi: 10.1016/j.omtn.2019.08.003. Epub 2019 Aug 12.
    lnc-3215 Suppression Leads to Calcium Overload in Selenium Deficiency-Induced Chicken Heart Lesion via the lnc-3215-miR-1594-TNN2 Pathway

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    Activation of Dusp14 protects against osteoclast generation and bone loss by regulating AMPKα-dependent manner

  4. Life Sci. 2019 Oct 15;235:116822.doi: 10.1016/j.lfs.2019.116822. Epub 2019 Aug 30.
    Effects of MFHAS1 on cognitive impairment and dendritic pathology in the hippocampus of septic rats

  5. Neurobiol Dis.2019 Sep;129:144-158. doi: 10.1016/j.nbd.2019.05.004.
    RIP3 participates in early brain injury after experimental subarachnoid hemorrhage in rats by inducing necroptosis

  6. Nat Commun. 2019 Sep 20;10(1):4303.doi: 10.1038/s41467-019-12351-x.
    Inactivation of NF-κB2 (p52) restrains hepatic glucagon response via preserving PDE4B induction.

  7. Cell Death Dis. 2019 Sep 11;10(9):670.doi: 10.1038/s41419-019-1873-x.
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    Regulation of response to radiotherapy by β-arrestin1 in Non-small cell lung cancer

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  12. Osteoarthritis Cartilage . 2019 Jun;27(6):922-931. doi:10.1016/j.joca.2019.01.012.
    Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB

  13. EBioMedicine.2019 Jun;44:439-451. doi: 10.1016/j.ebiom.2019.05.041
    MicroRNA-200b is downregulated and suppresses metastasis by targeting LAMA4 in renal cell carcinoma

  14. Neuroscience . 2019 Jun 15;409:43-57. doi: 10.1016/j.neuroscience.2019.04.041.
    NEMO-binding domain peptides alleviate perihematomal inflammation injury after experimental intracerebral hemorrhage

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    GATA-4 regulates neuronal apoptosis after intracerebral hemorrhage via the NF-κB/Bax/Caspase-3 pathway both in vivo and in vitro

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    Metabolic modulation of acetaminophen-induced hepatotoxicity by osteopontin

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    Dextran-Conjugated Caged siRNA Nanoparticles for Photochemical Regulation of RNAi-Induced Gene Silencing in Cells and Mice

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    Effects of microrna-93 on mouse cardiac microvascular endothelial cells injury and inflammatory response by mediating SPP1 through the NF-ΚB pathway

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    Global profiling of megalocytivirus-induced proteins in tongue sole (Cynoglossus semilaevis) spleen identifies cellular processes essential to viral infection

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    Blocking of tripartite motif 8 protects against lipopolysaccharide (LPS)-induced acute lung injury by regulating AMPKα activity

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    Fusobacterium nucleatum promotes chemoresistance to 5-fluorouracil by upregulation of BIRC3 expression in colorectal cancer

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    Inhibition of Lats1/p‐YAP1 pathway mitigates neuronal apoptosis and neurological deficits in a rat model of traumatic brain injury.

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    miR-34b-5p inhibition attenuates lung inflammation and apoptosis in an LPS-induced acute lung injury mouse model by targeting progranulin

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    The role of microRNA-146a in regulating the expression of IRAK1 in cerebral ischemia-reperfusion injury.

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    Overexpression of DNMT1 leads to hypermethylation of H19 promoter and inhibition of Erk signaling pathway in disuse osteoporosis

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    Hypoxia-inducible Factor-1α directs renal regeneration induced by decellularized scaffolds.

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    Long Non-coding RNA BC168687 is Involved in TRPV1-mediated Diabetic Neuropathic Pain in Rats.

  37. Purinergic Signal. 2018 Mar;14(1):47-58.doi: 10.1007/s11302-017-9594-z. Epub 2017 Nov 20.
    P2Y 12 receptor upregulation in satellite glial cells is involved in neuropathic pain induced by HIV glycoprotein 120 and 2′,3′-dideoxycytidine

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    Circular siRNAs for Reducing Off-Target Effects and Enhancing Long-Term Gene Silencing in Cells and Mice

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    Critical role for Annexin A7 in secondary brain injury mediated by its phosphorylation after experimental intracerebral hemorrhage in rats

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    Neuroprotection Exerted by Netrin-1 and Kinesin Motor KIF1A in Secondary Brain Injury following Experimental Intracerebral Hemorrhage in Rats.

  41. Evid Based Complement Alternat Med. 2018 Jan 9;2018:6139372.doi: 10.1155/2018/6139372. eCollection 2018.
    The Protective Effect of Total Flavones from Rhododendron simsii Planch. on Myocardial Ischemia/Reperfusion Injury and Its Underlying Mechanism.

  42. Cell Death Dis. 2018 Jan 9;9(1):11.doi: 10.1038/s41419-017-0014-7.
    miRNA-3473b contributes to neuroinflammation following cerebral ischemia.

  43. Exp Cell Res. 2017 Dec 15;361(2):342-352.doi: 10.1016/j.yexcr.2017.11.002. Epub 2017 Nov 2.
    Erythropoietin ameliorates early brain injury after subarachnoid haemorrhage by modulating microglia polarization via the EPOR/JAK2-STAT3 pathway.

  44. Cell Death Dis. 2017 Dec 13;8(12):3211.doi: 10.1038/s41419-017-0047-y.
    Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate ischemic neuronal death by targeting miR-21/PDCD4 signaling pathway

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    Regulation of Sirtuin 3-Mediated Deacetylation of Cyclophilin D Attenuated Cognitive Dysfunction Induced by Sepsis-Associated Encephalopathy in Mice.

  46. Chem Sci. 2017 Oct 19;9(1):44-51.doi: 10.1039/c7sc03842a. eCollection 2018 Jan 7.
    Caged circular siRNAs for photomodulation of gene expression in cells and mice

  47. Neurol Res. 2017 Sep;39(9):795-802.doi: 10.1080/01616412.2017.1321710. Epub 2017 May 1.
    The 15-LO-1/15-HETE system promotes angiogenesis by upregulating VEGF in ischemic brains.

  48. J Neurochem. 2017 Aug;142(3):478-492.doi: 10.1111/jnc.14075. Epub 2017 Jun 20.
    Tumor necrosis factor receptor-associated factor 6 participates in early brain injury after subarachnoid hemorrhage in rats through inhibiting autophagy and promoting oxidative stress

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    Targeting long non-coding RNA ASBEL with oligonucleotide antagonist for breast cancer therapy

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    Involvement of Toll Like Receptor 2 Signaling in Secondary Injury during Experimental Diffuse Axonal Injury in Rats.

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    Fluvastatin Prevents Lung Adenocarcinoma Bone Metastasis by Triggering Autophagy.

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    Limb remote ischaemic postconditioning-induced elevation of fibulin-5 confers neuroprotection to rats with cerebral ischaemia/reperfusion injury: Activation of the AKT pathway

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    Osteoblasts support megakaryopoiesis through production of interleukin 9.

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    MicroRNA-423-5p facilitates hypoxia/reoxygenation-induced apoptosis in renal proximal tubular epithelial cells by targeting GSTM1 via endoplasmic reticulum stress

  55. Can J Physiol Pharmacol. 2017 Apr;95(4):437-442.doi: 10.1139/cjpp-2016-0248. Epub 2016 Nov 24.
    miR-29b promotes skin wound healing and reduces excessive scar formation by inhibition of TGF-β1/Smad/CTGF signaling pathway.

  56. J Bone Miner Res. 2017 Feb;32(2):319-332.doi: 10.1002/jbmr.2992. Epub 2017 Jan 3.
    TET3 Mediates Alterations in the Epigenetic Marker 5hmC and Akt pathway in Steroid-Associated Osteonecrosis

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    Role of miR-145 in chronic constriction injury in rats.

  58. Int Immunopharmacol. 2016 Nov;40:339-346.doi: 10.1016/j.intimp.2016.09.011. Epub 2016 Sep 24.
    Fine-tuning the expression of microRNA-155 controls acetaminophen-induced liver inflammation

  59. Genet Test Mol Biomarkers. 2016 Nov;20(11):645-653.doi: 10.1089/gtmb.2016.0011. Epub 2016 Sep 27.
    Upregulation of miR-98 Inhibits Apoptosis in Cartilage Cells in Osteoarthritis.

  60. J Cell Sci. 2016 Nov 15;129(22):4305-4316.doi: 10.1242/jcs.189944. Epub 2016 Sep 26.
    HMGB2 regulates satellite-cell-mediated skeletal muscle regeneration through IGF2BP2

  61. Exp Eye Res. 2016 Oct;151:134-41.doi: 10.1016/j.exer.2016.08.010. Epub 2016 Aug 25.
    CD25 siRNA induces Treg/Th1 cytokine expression in rat corneal transplantation models

  62. Arthritis Rheumatol. 2016 Sep;68(9):2232-43.doi: 10.1002/art.39725.
    MiR-130b ameliorates murine lupus nephritis through targeting type I interferon pathway on resident renal cells.

  63. J Cardiovasc Pharmacol Ther. 2016 Sep;21(5):471-7.doi: 10.1177/1074248415624158. Epub 2016 Feb 4.
    The PTEN/Akt Signaling Pathway Mediates Myocardial Apoptosis in Swine After Coronary Microembolization

  64. Int J Clin Exp Pathol 2016;9(3):3125-3133
    Original Article Regulation of ZNF580 in pathogenesis of ischemic cerebrovascular disease accompanied with upregulation of Smad2 and ADNP

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    Transient receptor potential channel 1/4 reduces subarachnoid hemorrhage-induced early brain injury in rats via calcineurin-mediated NMDAR and NFAT dephosphorylation.

  66. Cell Physiol Biochem. 2016;38(1):207-19.doi: 10.1159/000438622. Epub 2016 Jan 20.
    Atorvastatin Inhibits Myocardial Apoptosis in a Swine Model of Coronary Microembolization by Regulating PTEN/PI3K/Akt Signaling Pathway.

  67. Cell Physiol Biochem. 2016;38(2):836-46.doi: 10.1159/000443038. Epub 2016 Feb 24.
    Upregulation of Long Non-Coding RNA PlncRNA-1 Promotes Metastasis and Induces Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma.

  68. Int J Mol Med. 2016 Jul;38(1):113-22.doi: 10.3892/ijmm.2016.2619. Epub 2016 May 31.
    miR-1 suppresses the growth of esophageal squamous cell carcinoma in vivo and in vitro through the downregulation of MET, cyclin D1 and CDK4 expression.

  69. Int J Biochem Cell Biol. 2016 Jun;75:11-22.doi: 10.1016/j.biocel.2016.03.008. Epub 2016 Mar 18.
    Inhibitory effects of omega-3 fatty acids on early brain injury after subarachnoid hemorrhage in rats: Possible involvement of G protein-coupled receptor 120/β-arrestin2/TGF-βactivated kinase-1 binding protein-1 signaling pathway.

  70. Oncotarget. 2016 Jun 14;7(24):37192-37204.doi: 10.18632/oncotarget.9293.
    Bmi1 inhibition enhances the sensitivity of pancreatic cancer cells to gemcitabine

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    Molecular characterization of woodchuck IFI16 and AIM2 and their expression in woodchucks infected with woodchuck hepatitis virus (WHV)

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    BMPR2-pSMAD1/5 signaling pathway regulates RUNX2 expression and impacts the progression of dedifferentiated chondrosarcoma

  73. Arthritis Rheumatol. 2016 Apr;68(4):953-64.doi: 10.1002/art.39485.
    In Vivo Therapeutic Success of MicroRNA‐155 (miR‐155) Antagomir in a Mouse Model of Lupus Alveolar Hemorrhage.

  74. Mol Brain. 2016 Apr 23;9:44.doi: 10.1186/s13041-016-0226-2.
    LncRNA NONRATT021972 siRNA regulates neuropathic pain behaviors in type 2 diabetic rats through the P2X7 receptor in dorsal root ganglia.

  75. Med Sci Monit. 2016 Apr 7;22:1161-70.doi: 10.12659/msm.897909.
    MiR-206 Attenuates Denervation-Induced Skeletal Muscle Atrophy in Rats Through Regulation of Satellite Cell Differentiation via TGF-β1, Smad3, and HDAC4 Signaling.

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    MiR-3162-3p Is a Novel MicroRNA That Exacerbates Asthma by Regulating β-Catenin.

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    Rictor Regulates Spermatogenesis by Controlling Sertoli Cell Cytoskeletal Organization and Cell Polarity in the Mouse Testis.

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    Effects of CD25siRNAgene transfer on high-risk rat corneal graft rejection.

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    Cyclophilin A/Cluster of Differentiation 147 Interactions Participate in Early Brain Injury After Subarachnoid Hemorrhage in Rats.

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    MicroRNA-125b attenuates epithelial-mesenchymal transitions and targets stem-like liver cancer cells through small mothers against decapentaplegic 2 and 4

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    MiR-346 regulates CD4+CXCR5 + T cells in the pathogenesis of Graves’ disease.

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    Macrophages promote benzopyrene-induced tumor transformation of human bronchial epithelial cells by activation of NF-κB and STAT3 signaling in a bionic airway chip culture and in animal models.

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    Sialyltransferase7A, a Klf4-responsive gene, promotes cardiomyocyte apoptosis during myocardial infarction.

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    ENTPD5 Induces Apoptosis in Lung Cancer Cells via Regulating Caspase 3 Expression.

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    Targeting LunX inhibits non-small-cell lung cancer growth and metastasis.

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    Mechanism of programmed cell death factor 4/nuclear factor-κB signaling pathway in porcine coronary micro-embolization-induced cardiac dysfunction.

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    NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model.NLRP1

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    BMPR2 inhibition induced apoptosis and autophagy via destabilization of XIAP in human chondrosarcoma cells.

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    Let-7d suppresses growth, metastasis, and tumor macrophage infiltration in renal cell carcinoma by targeting COL3A1 and CCL7.

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    Amyloid-β induces NLRP1-dependent neuronal pyroptosis in models of Alzheimer’s disease.

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    IL12/23 p40 Inhibition Ameliorates Alzheimer’s Disease-Associated Neuropathology and Spatial Memory in SAMP8 Mice.

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    Inhibition of IL-2 inducible T-cell kinase alleviates T-cell activation and murine myocardial inflammation associated with CVB3 infection.

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    Autophagic effect of programmed cell death 5 (PDCD5) after focal cerebral ischemic reperfusion injury in rats.

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    Trichinella spiralis excretory-secretory products protect against polymicrobial sepsis by suppressing MyD88 via mannose receptor.

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    MicroRNA-155 Modulates Th1 and Th17 Cell Differentiation and is Associated with Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis.

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    Heme Oxygenase-1 Exerts a Protective Role in Ovalbumin-induced Neutrophilic Airway Inflammation by Inhibiting Response in the Immune Cells Th17.

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    Sensory-sympathetic coupling in superior cervical ganglia after myocardial ischemic injury facilitates sympathoexcitatory action via P2X7 receptor.

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    The Involvement of Programmed Cell Death 5 (PDCD5) in the Regulation of Apoptosis in Cerebral Ischemia/Reperfusion Injury.

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    MicroRNAs (miRNAs) in colorectal cancer: From aberrant expression towards therapy.

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    Transdermal siRNA-TGFβ1-337 patch for hypertrophic scar treatment.

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    SirT1 mediates hyperbaric oxygen preconditioning-induced ischemic tolerance in rat brain.

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    Epub 2011 Oct 5.NIRF is frequently upregulated in colorectal cancer and its oncogenicity can be suppressed by let-7a microRNA.

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    Anti-Virus Research on Short Double-Stranded RNA in Mouse Models with Viral Myocarditis.

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